خلاصه داستان : داستان فیلم در بازه زمانی رخ می دهد که یک بیماری همه گیر در سیاره زمین پخش شده و اکنون تنهای جای امن، آسمان و ارتفاعات است.

England has been overrun by a pandemic with no apparent cure. As the infection continues to spread, safety - for a lucky few - looms in the form of a damaged 747 set to seek solace abroad. It's only once the plane is airborne that the survivors discover the infection made it onto the flight with them.